CHM 236IN - General Organic Chemistry II [SUN# CHM 2236]

4 Credits, 6 Contact Hours
3 lecture periods 3 lab periods

Continuation of CHM 235IN . Includes remaining classes of organic compounds, specifically dienes, alcohols, ethers and epoxides, aldehydes, ketones, acids, acid derivatives, aromatics, and nitrogen containing compounds and an introduction to biomolecules and/or polymers. Also includes an emphasis on synthesis and use of chemical and instrumental methods as means of identification while using a wide range of laboratory apparatus and procedures. Also focuses on laboratory safety skills and computer software applications related to chemistry.

Prerequisite(s): CHM 235IN  with a grade of C or better. 
Gen-Ed: Meets AGEC - SCI; Meets CTE - M&S.

1. Construct synthetic schemes by which a variety of organic compounds may be prepared from simple, readily available starting materials.
2. Deduce the structural formula of a given or unknown organic compound from spectroscopic (IR, MS and NMR) or chemical reactivity data.
3. Demonstrate an understanding of 2-dimensional and 3-dimensional structure through use of organic drawing software and molecular modeling.

1. Given the structural formula or name of a large assortment of organic compounds, predict:
   1. the detailed 2-dimensional and 3-dimensional structure of a molecule;
   2. the reaction products arising from treatment with a variety of reagents;
   3. the way in which bonds are made and broken to bring about product formation in these reactions;
   4. the effect of structural alterations on reactivity (rate or position of equilibrium) in these reactions;
   5. fundamental physical properties of an organic compound.
2. Construct synthetic schemes by which a variety of organic compounds may be prepared from simple, readily available starting materials.
3. Deduce the structural formula of a given or unknown organic compound from spectroscopic (IR, MS and NMR) or chemical reactivity data.
4. Demonstrate knowledge of sources and/or uses for organic compounds in the practical world.
5. Apply the principles of organic chemistry to larger biomolecules and polymers.
6. Demonstrate an understanding of 2-dimensional and 3-dimensional structure through use of organic drawing software and molecular modeling.
7. Apply the above chemistry concepts and procedures in a “wet” laboratory setting with real laboratory equipment to:
   1. continue the development of  hands-on experience with a wide range of laboratory apparatus;
   2. continue to gain exposure to the hands-on use of chemical instrumentation;
   3. further individual expertise in a range of organic laboratory techniques.
8. Apply microscale organic synthesis, laboratory safety skills and computer software skills as related to chemistry.

1. Conjugated Dienes and Ultraviolet Spectroscopy
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Ultraviolet spectroscopy
      1. theory
      2. analysis of conjugated dienes
2. Study of Aromatics
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
3. Study of Alcohols and Phenols
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
4. Study of Ethers and Epoxides
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
5. Study of Aldehydes and Ketones
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
6. Study of Carboxylic Acids and Nitriles
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
7. Study of Derivatives of Carboxylic Acids (acid halides, anhydrides, amides and esters)
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
8. Study of Amines
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
9. Study of Biomolecules (carbohydrates, amino acids, peptides and proteins, lipids, heterocycylic and nucleic acids)*
   1. Physical attributes
      1. structure
      2. nomenclature
      3. physical properties
   2. Chemistry of organic molecules                   
      1. preparations
      2. reactions
      3. reaction mechanisms
      4. stereochemistry
      5. synthetic procedures
      6. industrial applications
      7. connections to biochemistry/polymers/real world applications
   3. Analysis of organic molecules – spectroscopy
      1. infrared
      2. nuclear magnetic resonance
      3. mass spectroscopy
      4. pertinent metabolic pathways
10. Study of Polymers*
    1. Physical attributes
       1. structure
       2. nomenclature
       3. physical properties
    2. Chemistry of organic molecules        
       1. preparations
       2. reactions
       3. reaction mechanisms
       4. stereochemistry
       5. synthetic procedures
       6. industrial applications
       7. connections to biochemistry/polymers/real world applications
    3. Analysis of organic molecules – spectroscopy
       1. infrared
       2. nuclear magnetic resonance
       3. mass spectroscopy
       4. Pertinent metabolic pathways
11. Fundamental Techniques in Synthesizing a Compound to Create a Synthetic Product
    1. Methods of heating reaction mixtures
    2. Reflux
    3. Distillation
    4. Extraction and isolation
    5. Vacuum filtration
    6. Recrystalization
12. Characterization of Organic Molecules
    1. Melting point and/or boiling point determination
    2. Spectroscopy (IR, NMR and MS) based on availability of equipment
    3. Refractometry
    4. Polarimetry
    5. Chromatography (TLC and/or GC) based on availability of equipment
13. Integrated Generally Applied Laboratory Procedures
    1. Microscale organic synthesis
    2. Laboratory safety skills
    3. Related computer software application
       1. Development of technical writing skills through keeping a laboratory experiment notebook and writing lab reports
       2. Other computer skills related to chemistry including Molecular Modeling and organic drawing software

 
*One or more of the topics under Roman Numerals IX and X should be introduced at the discretion of the instructor.