2021-2022 College Catalog [ARCHIVED CATALOG]
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PHT 182 - Drug Therapy II 4 Credits, 4 Contact Hours
4 lecture periods 0 lab periods
Continuation of PHT 172 . Relationship between anatomy and physiology, disease states, and pharmaceutical therapy. Includes origins, dosage forms, indications, actions, routes of administration and side effects of both prescription and non-prescription drugs used in diseases of the cardiovascular, circulatory, renal, endocrine, respiratory, digestive, reproductive, and integumentary systems.
Prerequisite(s): PHT 172
Course Learning Outcomes
- Identify characteristics of the anatomy and physiology of the cardiovascular, circulatory, renal, endocrine, respiratory, digestive, reproductive, and integumentary systems.
- Identify disorders and disease states of the cardiovascular, circulatory, renal, endocrine, respiratory, digestive, reproductive, and integumentary systems.
- Identify and list drugs needed to treat specific disorders and disease states of the cardiovascular, circulatory, renal, endocrine, respiratory, digestive, reproductive, and integumentary systems.
- List characteristics of each drug, including: indications for use; dosage form(s); usual dosage; side effects and toxicity; interaction with other drugs; storage requirements; special preparation procedures; generic/trade name; and mechanisms of action.
- Practice effective control procedures, including preventing transmission of blood borne and airborne diseases.
Outline:
I Introduction
- Cardiovascular System
A. Anatomy and physiology of the heart and blood vessels
B. Diseases of the heart and blood vessels
1. Arrhythmias
2. Congestive heart failure
3. Coronary artery disease
4. Hypertension
5. Infections
C. Drugs used to treat cardiovascular disease
D. Specific characteristics of drugs for cardiovascular diseases
- Indications for use
- Dosage form(s)
- Usual dosage
- Side effects and toxicity
- Significant drug interactions
- Storage requirements
- Special preparation procedures
- Mechanisms of action
III. Circulatory/Reticuloendothelial System
A. Anatomy and physiology of the circulatory/reticuloendothelial system
1. Blood
2. Lymphatic system
3. Blood-forming organs
B. Diseases involving the blood elements and clotting mechanisms
1. Erythrocyte disorders
2. Leukocyte disorders
3. Acquired Immune Deficiency Syndrome (AIDS)
4. Hemorrhaghic disorders
5. Hyperlipoproteinemia
C. Drugs affecting the circulatory/reticuloendothelial system
1. Drugs used in the treatment of anemias
2. Drugs altering blood coagulation
3. Drugs used to treat hyperlipidemias
4. Drugs used in the chemotherapy of hematologic malignancies
IV. Renal System
A. Anatomy and physiology of the kidney
1. Blood circuit
2. Tubular urine circuit
3. Factors influencing diuresis functions of the kidney
B. Functions of the kidney
1. Excretion of waste
2. Acid-base balance
3. Water balance
4. Electrolyte balance
5. Renin secretion
C. Diseases treated with diuretic drugs
1. Edematous conditions
2. Nonedematous conditions
D. Disorders treated with uricosuric drugs - gout
E. Drugs affecting the renal system
1. Diuretic drugs
2. Uricosuric drugs
F. Special aspects of electrolyte patterns seen in diuretic therapy
1. Hypokalemia
2. Hyperkalemia
3. Hyponatremia
4. Hyperchloremia
G. Factors involved in the clinical selection of a suitable diuretic drug
H. Specific characteristics of drugs prescribed for various kidney disorders
1. Indications for use
2. Dosage form(s)
3. Usual dosage
4. Side effects and toxicity
5. Significant drug interactions
6. Storage requirements
7. Special preparation procedures
8. Generic/trade names
9. Mechanisms of action
V. Endocrine System
A. Anatomy and physiology of the endocrine system
1. Pituitary gland
2. Thyroid gland
3. Parathyroid glands
4. Adrenal glands
5. Gonads
6. Pancreas
B. Special aspects of endocrine glands
C. Dysfunction of the endocrine glands
1. Anterior pituitary gland
2. Posterior pituitary gland
3. Thyroid gland
4. Parathyroid glands
5. Adrenal glands
6. Gonads
7. Pancreas
D. Drugs affecting the endocrine system
1. Anterior pituitary hormones
2. Posterior pituitary preparations
3. Thyroid gland preparations
4. Antithyroid drugs
5. Thyroid parafollicular C cell hormone
6. Parathyroid gland preparations
7. Adrenal gland preparations
8. Sex hormone preparations
9. Pancreatic preparations
E. Specific characteristics of drugs of the endocrine system
1. Indications for use
2. Dosage form(s)
3. Usual dosage
4. Side effects and toxicity
5. Significant drug interactions
6. Storage requirements
7. Special preparation procedures
8. Generic/trade names
9. Mechanisms of action
VI. Respiratory System
A. Anatomy and physiology of the respiratory system
B. Disorders of the respiratory system
1. Allergy
2. Diseases/disorders of the nose, throat, ear
3. Chronic Obstructive Pulmonary Disease
4. Bacterial/viral infectious diseases of the lower respiratory tract.
5. Infectious fungal disease
6. Pulmonary tumors
C. Drugs used in respiratory disorders and infections
1. Antihistamines; Hl receptor blockers
2. Antibacterial drugs
3. Antibacterial drugs that affect cell wall synthesis
4. Antibacterial drugs that affect protein synthesis
5. Antibacterial drugs that act primarily as antimetabolites
6. Antimicrobial drugs that alter plasma membrane permeability
D. Drugs used in lung carcinoma
E. Specific characteristics of drugs of respiratory system
1. Indications for use
2. Dosage form(s)
3. Usual dosage
4. Side effects and toxicity
5. Significant drug interactions
6. Storage requirements
7. Special preparation procedures
8. Generic/trade names
9. Mechanisms of action
VII. Digestive/Gastrointestinal System
A. Anatomy and physiology of the digestive/gastrointestinal system.
1. Mouth and esophagus
2. Stomach
3. Small intestine
4. Colon
5. Additional organs vital to digestion
B. Disorders of the digestive/gastrointestinal system
1. Disorders of the mouth/salivary glands
2. Esophageal disorders
3. Stomach disorders
4. Intestinal disorders
5. Liver disorders
6. Liver disorders
7. Gallbladder disorders
8. Pancreatic disorders
C. Drugs used in the treatment of digestive/gastrointestinal system disorders
1. Drugs used in the treatment of peptic ulcer
2. Laxatives
3. Digestive aids
4. Antidiarrheals
5. Miscellaneous gastrointestinal drugs
6. Antihemorrhoid preparations
7. Antiemetics
8. Antibiotics/antiinfectives used in gastrointestinal infections
9. Antineoplastics
10. Anthelmintics
D. Specific characteristics of drugs of the digestive/gastrointestinal tract.
1. Indications for use
2. Dosage form(s)
3. Side effects and toxicity
4. Side effects and toxicity
5. Significant drug interactions
6. Storage requirements
7. Special preparation procedures
8. Generic/trade names
9. Mechanisms of action
VIII. Reproductive/Genitourinary System
A. Anatomy and physiology of the reproductive/genitourinary system
1. Female genital system
2. Make genital system
3. Renal/urinary excretion system
B. Diseases and disorders of the genitourinary system
1. Venereal infections
2. Nonvenereal infections
3. Carcinomas of the female reproductive system
4. Carcinomas of the male reproductive system
5. Carcinomas of the urinary bladder
C. Drugs used in the treatment of genitourinary diseases and infections
1. Drugs used to treat infections
2. Drugs that affect uterine musculature
3. Antineoplastic drugs
D. Specific characteristics of drugs of the reproductive/genitourinary system
1. Indications for sue
2. Dosage form(s)
3. Usual dosage
4. Side effects and toxicity
5. Significant drug interactions
6. Storage requirements
7. Special preparation procedures
8. Generic/trade names
9. Mechanisms of action
IX. Integumentary/Connective Tissue System
A. Anatomy and physiology of the integumentary/connective tissue system
1. Connective tissue
2. Functions of the skin
3. Sweat glands
4. Skin appendages
B. Diseases and disorders of the integumentary/connective tissue system
1. Skin infections
2. Skin infestations
3. Miscellaneous skin disorders
4. Skin cancers
5. Disorders of the joints and connective tissues
C. Drugs used in the treatment of integumentary/connective tissue disorders
1. Drugs used to treat skin diseases
2. Drugs used to treat diseases of the joints and connective tissues
D. Specific characteristics of drugs of the integumentary/connective tissue systems
1. Indications for use
2. Dosage form(s)
3. Usual dosage
4. Side- effects and toxicity
5. Significant drug interactions
6. Storage requirements
7. Special preparation procedures
8. Generic/trade names
9. Mechanisms of action
10. Excretion of waste
X. Transmission risks healthcare worker to patient & patient to patient
1. Risks
2. Hepatitis
3. HIV
4. Other
XI. Transmission of airborne diseases
- Risks
- Prevention
- Social & respiratory etiquette
Effective Term:
Fall 2015
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