MLT 230IN - Immunohematology and Immunology

5 Credits, 7 Contact Hours
4 lecture periods 3 lab periods
Introduction to basic immunology related to methods utilized in the clinical laboratory. Includes blood collection, blood components, immunology and complement, principles of serological testing, genetics, blood group systems, antiglobulin testing, gel and solid phase testing, and identification of unexpected antibodies. Also includes neonatal and obstetrical transfusion practice, pre-transfusion compatibility testing, International Society of Blood Transfusion (ISBT) product labeling, adverse effects of blood transfusions, positive direct antiglobulin test (DAT), immune hemolysis, quality assurance, transplantation, and molecular testing.

Prerequisite(s): With a grade of B or better: BIO 205IN , and MAT 151  or assessment intoMAT 189 .
Information: Students must be admitted to the Medical Laboratory Technician program or obtain consent of instructor before enrolling in this course.
    

2.   Identify, define, and distinguish the immune processes as they relate to immunohematology and the       characteristics of antigens and antibodies of the ABO, Rh, and other blood group systems.

3,   Obtain accurate results using a variety of methods on samples including ABO, Rh, DAT, IAT, crossmatch,       phenotype (and control selection), donor selection; and test for adverse effects of transfusions. 

4.   Identify units, reagents and samples using standard labeling practices.

5.   Improve critical thinking and organizational skills by attending class, completing assignments, and      participating in problem solving discussions.

1. Blood Collection
2. Blood and Blood Components
3. Immunology and Complement
4. Principles of Serological Testing in Immunohematology
5. Genetics
6. ABO and H Blood Group Systems
7. Rh Blood Group System
8. Other Blood Group Systems
9. Antiglobulin Testing
10. Gel and Solid Phase Testing
11. Identification of Unexpected Antibodies
12. Neonatal and Obstetrical Transfusion Practice
13. Pre-Transfusion Compatibility Testing
14. International Society of Blood Transfusion (ISBT) Product Labeling
15. Adverse Effects of Blood Transfusion
16. Investigation of the Positive Direct Antiglobulin Test (DAT) and Immune Hemolysis
17. Quality Assurance
18. Transplantation
19. Molecular Testing