Apr 14, 2026  
2026-2027 College Catalog 
    
2026-2027 College Catalog

CRC 240 - Pharmacology for Clinical Trials

4 Contact Hours, 4 Credits
4 lecture periods 0 lab periods


Essential drug knowledge and their application in clinical research. Includes common medical diagnoses and their related drug treatments; what constitutes a drug; the effects and modes of action of drugs upon the body (pharmacodynamics); method and rate of excretion and duration of the effect of drugs (pharmacokinetics); drug adverse reactions; drug-drug interactions; and how medication information is used to screen for clinical trial eligibility and continuity of participant safety.

Information: Students must be admitted to or have conditional status of the Clinical Research AAS or Post-Degree Certificate program or obtain the consent of the instructor before enrolling in this course.
Button linking to AZ Transfer course equivalency guide    button image Prior Learning and link to PLA webpage

Course Learning Outcomes
  1. Apply pharmacology terminology in the context of clinical trial documentation
  2. Explain the principles of clinical pharmacokinetics and pharmacodynamics
  3. Discuss factors that influence clinical pharmacokinetics and pharmacodynamics
  4. Research drug-related information from reference sources.
  5. Categorize drugs based on indication, mechanism of action, drug actions and side effects.
  6. Explore the principles of pharmacogenomics

Outline:
  1. Pharmacokinetics
    1. Half-life
    2. Drug Vehicle
    3. Therapeutic range
    4. Steady-state
    5. Bioavailability
    6. Routes of administration
    7. Absorption, distribution, metabolism and excretion (ADME)
  2. Pharmacodynamics
    1. Effects of drug
    2. Mechanism of drug action
    3. Dose and concentration response
    4. Selectivity of drug action
    5. Polypharmacology
  3. General Concepts and Terminology
    1. Drug Classification
    2. Polypharmacy
    3. Drug-Drug Interaction
    4. Pharmacogenomics
    5. Prodrugs
  4. Adverse Reactions
    1. Reactions
      1. Adverse reactions
      2. Serious adverse reactions
  5. Common pathophysiology and pharmacology 
    1. Cardiovascular System
    2. Respiratory System
    3. Endocrine System
    4. Urinary System
    5. Immune System
    6. Nervous System